Role of mitotic replication genes in chromosome duplication during meiosis.
نویسندگان
چکیده
منابع مشابه
Initiation of homologous chromosome pairing during meiosis.
Following pre-meiotic DNA replication, homologous chromosomes must be paired and become tightly linked to ensure reductional segregation during meiosis I. Therefore initiation of homologous chromosome pairing is vital for meiosis to proceed correctly. A number of factors contribute to the initiation of homologous chromosome pairing including telomere and centromere dynamics, pairing centres, ch...
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The NH 2 -terminal domain (N-tail) of histone H3 has been implicated in chromatin compaction and its phosphorylation at Ser10 is tightly correlated with mitotic chromosome condensation. We have developed one mAb that specifically recognizes histone H3 N-tails phosphorylated at Ser10 (H3P Ab) and another that recognizes phosphorylated and unphosphorylated H3 N-tails equally well (H3 Ab). Immunoc...
متن کاملControl of the mitotic exit network during meiosis
The mitotic exit network (MEN) is an essential GTPase signaling pathway that triggers exit from mitosis in budding yeast. We show here that during meiosis, the MEN is dispensable for exit from meiosis I but contributes to the timely exit from meiosis II. Consistent with a role for the MEN during meiosis II, we find that the signaling pathway is active only during meiosis II. Our analysis furthe...
متن کاملChromosome Dynamics in Meiosis
Meiosis encompasses a large number of dynamic processes. Some of them are biochemical, such as formation and repair of meiotic double-strand breaks, while others are physical in nature, such as homologous chromosome segregation in anaphase I. Plants have been used as model species in meiosis studies for over 80 years. However, the past decade brought a dramatic improvement in the understanding ...
متن کاملThe Dynamics of Homologous Chromosome Pairing during Male Drosophila Meiosis
BACKGROUND Meiotic pairing is essential for the proper orientation of chromosomes at the metaphase plate and their subsequent disjunction during anaphase I. In male Drosophila melanogaster, meiosis occurs in the absence of recombination or a recognizable synaptonemal complex (SC). Due to limitations in available cytological techniques, the early stages of homologous chromosome pairing in male D...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1977
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.74.9.3951